Video by Declan Taylor
Dillian Whyte will face Dereck Chisora in an explosive heavyweight match-up on the Anthony Joshua vs Eric Molina undercard.
Promoter Eddie Hearn has been looking to make the fight for some time, with Chisora stating last week he would not sign until his demands were met.
Whyte has rebounded from a sixth-round knockout defeat to Joshua with three consecutive wins, with his latest victory coming over Ian Lewison.
While Chisora picked up a win over journeyman Drazan Janjanin in September after a split decision defeat to Kubrat Pulev for the European title.
Whyte's only defeat came against Joshua, who will top the bill against American Molina - on paper the toughest test for the former Olympian in his professional career.
Scott Quigg will also make his return after suffering a broken jaw against Carl Frampton and the Bury fighter will move up, just like his rival Frampton, to the featherweight division.
“The Heavyweight division has been turned on its head in the last few months and while many are standing still waiting, I’m delighted to get this huge card up and running in Manchester,” said promoter Eddie Hearn.
“I have spoken to Eric Molina at length and I know this is going to be a big test for Anthony. We saw in the Wilder fight that he can punch and doesn’t give in and is coming off a strong knockout win against Adamek in his back yard in Poland.
"We have requested an exception from the IBF for this fight and although the plans are for a major unification in the spring this fight requires Anthony’s full focus.
“The card is one of the strongest we have produced, supported by a huge all-British Heavyweight grudge match between Dillian Whyte and Dereck Chisora which will be an official eliminator for the WBC World title."