Former two division world champion Bernard Hopkins is the benchmark for every boxer who wants to turn back the clock at the late stage.

Hopkins set a record, at age 46, by becoming the oldest fighter in boxing history to capture a world title. He broke his own record two years later, at age 48, by winning another light heavyweight title.

Manny Pacquiao, 42-years-old and the only eight division world champion in history, will make his own attempt to turn back the clock on August 21, when he challenges WBC, IBF welterweight champion Errol Spence.

Spence is undefeated, younger, stronger, a skilled boxer - and a solid favorite to win the fight with older Pacquiao.

Experts view Spence as one of the best pound-for-pound fighters in the sport.

However, Hopkins is not ruling out an upset win for the future Hall of Famer.

“The advantage mentally goes to Pacquiao,” said Hopkins to KO Artist Sports. “We all know as far as the experience goes, that along with a burst of youthful energy, that we’ve seen in history in fights where guys we knew were dangerous but we didn’t know he was gonna show up that good. That’s the type of feeling I get when I hear about this fight. There are fighters who’ve been around as long as Manny who’ve seen every style and have been in every hostile situation."

One of Pacquiao's best qualities is his footwork. 

To disrupt that footwork, Hopkins explains that Spence will have to be dedicated to his jab and use that punch as his primary weapon to control the fight.

“The jab is important and Spence has to control the jab. Because that jab disturbs you, it messes up the rhythm for the fighter to go. Pacquiao’s been great [with his quick movement] for 15 years and he’ll beat you with his legs first into submission and after that he hits you," Hopkins said.