Three division world champion Félix 'Tito' Trinidad is well aware of the atmosphere during a fight card at Madison Square Garden in New York.

The venue was the Puerto Rican star's second home, with six big bouts taking place at MSG.

On Saturday night, his countryman, Amanda “The Real Deal” Serrano, will collide with undisputed lightweight world champion Katie Taylor of Ireland.

It will mark the first time where two women will headline a card at Madison Square Garden.

“The mentality (of Serrano) should be the same one that she has carried for all her fights, which is to be very focused. She should have the mentality that she is going to fight to win. That should be the mindset of every fighter. We are not invincible, because I suffered three losses, but I always went up (in the ring) with the mentality of winning," Trinidad told Carlos Gonzalez.

It will not be the first time that Serrano (41-1, 30 KO) has found himself under the lights of Madison Square Garden, but not in the main event. In 2019, she fought Eva Voraberger and later faced Heather Hardy. Both of those fights were held in the at the Hulu Theater, a smaller venue within Madison Square Garden's complex with capacity for some 5,000 people. On Saturday, Serrano will headline the big room.

“I can say that there is a difference between being one of the prelims and being the main event fighter, because it carries more responsibility. It is the fight that we will all be watching, for the world title, and that Puerto Rico hopes will obtain that great victory. We know she will win," Trinidad said.

Trinidad was impressed with Serrano's work ethic. He had the opportunity to see her complete a training session in Puerto Rico.

“I saw her training at the gym in Cupey and it was very good. A lot of speed, the physical condition was excellent and that was three weeks ago. She will win and that's what I see that going down in the fight, she must impose herself and who knows [she might win] even by knockout."